News & Events
DHR's Latest Newsletter
We're excited to share all the lastest news about Down Home Ranch. Here's a quick preview of what we've included in the January 2014 edition of the Spirit Newsletter:
A Recent Post from the DHR Blog
When Kelly was five weeks old, the National Down Syndrome Congress convention came to San Antonio. Daughter Martha and I drove down to see what we could learn.
Jerry and I ... had also just received Kelly's karyotype, which showed, most curiously, four No. 21 chromosomes. This was, needless to say, worrisome to us (and unheard of to our physicians). If one extra chromosome could gum up the works, what would two do?
Fortunately, the very man who discovered the cause of Down syndrome was present at the conference.
Jérôme Lejuene was a French researcher, who in 1958 identified that an extra 21st chromosome caused the syndrome named after the man who first described it, John Langdon Down.
...I figured he would be interested in Kelly's karyotype, and I was interested in his take on it, so I stood in line to speak with him. Read the full article >>
DHR Is In the News!
Many thanks to TWC's Your News Now for kicking off their annual 12 Days of Giving series with Down Home Ranch.
Another Post from the DHR Blog
Jerry and I, three staff, and two Down Home Ranch Board members attended the National Down Syndrome Congress Conference (NDSC) in Denver in mid-June. Jerry and I went up early to attend the Global Down Syndrome Foundation Round Table on current advances in Down syndrome research and treatment.
Wow! What a difference a few years make! Down syndrome has traditionally been a subject few were willing to tackle in terms of research. The reasons are complex and varied.
First, there's the matter of an entire chromosome being involved, not a single gene, as in cystic fibrosis. It has only been in the last decade or so that researchers have been willing to tackle such a complicated and daunting task. Where to begin? Read the full article >>
Another Article Research on Down Syndrome
US researchers have found a way to reverse Down syndrome in newborn lab mice by injecting an experimental compound that causes the brain to grow normally.
The study, published in the Science Translational Medicine journal, offers no direct link to a treatment for humans but scientists are hopeful it may offer a path towards future breakthroughs.
There is no cure for Down syndrome, which is caused by the presence of an additional chromosome and results in intellectual disabilities, distinctive facial features and other health problems.
The team at Johns Hopkins University of Medicine, in Baltimore, used lab mice that were genetically engineered to have extra copies of about half the genes found on human chromosome 21, leading to Down syndrome-like conditions such as smaller brains and difficulty learning to navigate a maze. On the day the mice were born, scientists injected them with a small molecule known as a sonic hedgehog pathway agonist. Read the full article >>
Another Post from Judy's Blog
Yesterday I wrote about coming advancements in the possibility of medical intervention to overcome the disabling effects of Down syndrome in the brain. This was in the context of a promise to a family with a newborn with Downs.
Little did I realize...
In today's Wall Street Journal there is an article on page A3 entitled "New Attack on Alzheimer's." It reports the success researchers at Case Western Reserve have had in reversingnot preventingreversing advanced Alzheimer's in mice bred to develop the disease.
So? You may ask. Mice are not men and Alzheimer's is not Down syndrome. Read the full article >>
More News: Thanks for Spreading the Word!
Over the years, folks in the media have visited Down Home Ranch and shared wonderful stories, blog postings, news articles, and videos about us. The stories below will give you a flavor of where we've been and what we're doing now. Many thanks to these authors for sharing their stories and spreading the news about Down Home Ranch with others. If you'd like to catch up on the latest news and current projects at Down Home Ranch, check out the DHR Blog and our Facebook Page.
Down Home Ranch, 4/20/2012: Higgins unHinged blog author is a very special, very long-time friend of Jerry and Judy. He shares a bit of that personal history in this post, along with a description of the early days at Down Home Ranch.
My New Home Town, 3/21/2012: bean&noodle blog author lovingly describes her recent visit to Down Home Ranch, shares pictures and a video.
Advancing Down Syndrome Research, 3/21/2012: Texas' First Lady, Anita Perry, gives a nod to Down Home Ranch.
Down Home Ranch - 20 Years of Thanks, 4/18/2011, a video by Chris Hatcher
News 8 Austin, 12/21/10: Poinsettias Supply Down Home Ranchers with Holiday Spirit